Below are two generic errors in every version of IIS. If we deploy applications without few configuration or setting in Application Pool & ISPAI Extension these errors will comes up. There are few changes in IIS 7/ IIS 8 but process are same. After New installation of IIS and before deploying any Application I do below configuration in IIS 8/7 to remove these error. The requested content appears to be script and will not be served by the static file handler. or An ASP.NET setting has been detected that does not apply in Integrated managed pipeline mode.